Key milestones
2005
* Research at Danish Polymer Centre at Risř/DTU led to filing of core patent.
* IP carried through to PCT Phase.
2007
* Proof-of-concept in lab scale experiments.
* InMold Biosystems A/S was formed as a seed capital backed spin-out.
* IP entered into National Phase (World Wide).
2008
* Proof-of-production of commercial grade products.
* Management buy-out.
Raising of Angle financing.
* Moving to new facilities at Danish Technological Institute.
* Initiating the establishment of fully automated in-house pilot plant.
* Succesful comparison with commercially available coated products. We have proved superior product quality! and very competitive manufacturing cost.
* Filing of further patents to create a strong patent family around core technology and key applications.
* Initiating industrial partnerships
* Winner of the European Venture Contest Award 2008 in Barcelona (90.000 euro cash prize)
2009
* Establisment of QA/QC laboratory
* Successful raising of further equity capital
* Entering the Danish Gazelle Growth program
www.gazellegrowth.dk
* Upgrading pilot plant to manufacturing plant of commercial products |
InMold Biosystems is setting the new standard for protein coated plastic labware.
A novel IP protected technology allows biological molecules, deposited on the surface of a mold, to be transferred and integrated into the surface of injection molded plastic articles.
Further the protein coated products are finalisation sterilised, -without loss of biological functionality.
InMold technology is integrated within a fully automatable injection molding production line with high productivity, low manufacturing cost, and strict regulatory compliance, which brings unique advantages to the final coated plastic products;
- Homogeneously coating of only the bottom of the well
(other products may have coating up the side of the wells, as well as a lunar shaped bottom coating due to wet chamical coating and suction of excess proten solution)
- No leakage and high binding capacity
(other products may have leakage over time as well as lower binding capacity. These are paramount parameters e.g. within diagnostics)
- Arbitrary coating geometry
(Arrays or homogenously coated surfaces, as well as different proteins in wells are possible with InMold Biosystem technology, allowing easy development of new products. Mixing of protein and growth factor adds further functionality to the InMold products e.g. for stem cell applications).
- Beta/Gamma sterilisation of final coated product
(The unique ability to beta and gamma irradiate the final coated products ensures that products live up to new coming EU regulations for Advanced Cell Therypy Products)
We are bringing our products to the global market place in collaboration with a few industrial partners within:
- Cell Culture (disposable coated plastic labware)
- Diagnostics, (disposable coated plastic labware)
- Diagnostics, (microfluidics, POC)
Biological molecules demonstrated with our process so far, are within classes such as ligand binding proteins (Streptavidin, IgG), extra-cellular matrix proteins (Collagen, Fibronectin), growth factors (bFGF), enzymes, as well as mixes of the different molecule classes.
We have further experimented with thermoresponsive surfaces.
Molecules may be immobilised on larger flat or structured surface area, as array on slide or in wells, or as single spot in microchannel, - and a very dense and homogeneous reproduceable molecule immobilisation may be obtained.
InMold Biosystems has the capability, facility and competencies to to test our technology with customer specific biomolecules.
Information on IP, unique advantages of the final products and the process, as well as documentation related to testing of various molecules, polymers, and comparison with commercial products can be made available after signing NDA and material tranfer agreement. |
Contact
CEO
Henrik Dörge
Ph.D, M. Sc. MBA.
Direct: +45 22143822
CSO
Henrik Pranov
Ph.D, M. Eng.
Direct: +45 28141310
InMold Biosystems A/S
Gregersensvej
Port 28
2630 Taastrup
Denmark |
